How safe is pantoprazole?
How safe is pantoprazole?
PPI have minimal side effects and few slight drug interactions and are considered safe for long term treatment. Pantoprazole is significantly effective both for acute and long-term treatment with excellent control of relapse and symptoms. It is well tolerated even for long-term therapy and its tolerability is optimal.
Is pantoprazole a preventative drug?
It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Pantoprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).
Can pantoprazole cause problems?
Though it’s rare, pantoprazole can cause an allergic reaction. Symptoms may include rash, swelling, or breathing problems. This allergic reaction can progress to interstitial nephritis, a kidney disorder that can lead to kidney failure.
What are the side effects of pantoprazole sod EC?
What side effects can this medication cause?
- headache.
- nausea.
- vomiting.
- gas.
- joint pain.
- diarrhea.
- dizziness.
How long does pantoprazole last in your system?
Pantoprazole is extensively metabolized in the liver through the cytochrome P-450 system, predominantly by CYP2C19 demethylation with subsequent sulfation and has a serum elimination half-life of about 1.1 hours.
Is pantoprazole safer than Zantac?
In conclusion, pantoprazole was more effective than ranitidine in the healing rate and relief from reflux esophagitis-associated symptoms, and Hp infection was associated with higher healing rate during therapy with pantoprazole but not with ranitidine.
What is the side effect of pantoprazole 40 mg?
Common pantoprazole side effects may include: headache, dizziness; stomach pain, gas, nausea, vomiting, diarrhea; joint pain; or.
How old do you have to be to take pantoprazole sodium?
Pantoprazole sodium is used in children ages 5 years to 16 years old for short-term treatment (for up to 8 weeks) of acid-related damage to the lining of the esophagus (erosive esophagitis) caused by GERD. Pantoprazole sodium is not for children under 5 years old.
What is the bioavailability of pantoprazole 40 mg?
In the dose range of 10 to 80 mg, the plasma kinetics of pantoprazole are linear after both oral and intravenous administration. The absolute bioavailability from the tablet was found to be about 77 %. Concomitant intake of food had no influence on AUC, maximum serum concentration and thus bioavailability.
Are there any adverse reactions to pantoprazole sodium?
In clinical studies of Zollinger-Ellison Syndrome, adverse reactions reported in 35 patients taking pantoprazole sodium 80 mg/day to 240 mg/day for up to 2 years were similar to those reported in adult patients with GERD. The following adverse reactions have been identified during postapproval use of pantoprazole sodium.
How is pantoprazole sodium sesquihydrate soluble in water?
Pantoprazole sodium sesquihydrate is a white to off-white crystalline powder and is racemic. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium sesquihydrate is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane.
How safe is pantoprazole? PPI have minimal side effects and few slight drug interactions and are considered safe for long term treatment. Pantoprazole is significantly effective both for acute and long-term treatment with excellent control of relapse and symptoms. It is well tolerated even for long-term therapy and its tolerability is optimal. Is pantoprazole a…