What are Bisindole alkaloids?
What are Bisindole alkaloids?
Bisindole natural products consist of two monomeric indole alkaloid units as their obligate constituents. Bisindoles are more potent with respect to their biological activity than their corresponding monomeric units. The monomeric units belong to the sarpagine, ajmaline, macroline, vobasine, and pleiocarpamine series.
What is Bisindole?
Noun. bisindole (plural bisindoles) (organic chemistry) Any of several tetracyclic heterocycles consisting of two indole moieties linked by a single bond.
What is BIS indole?
Bisindoles are a class of natural products derived from oxidative dimerization of tryptophan, and many of these molecules have potential use as anticancer agents.
Which drug does not contains indole ring?
Havil (kratom), while the other two plants that did not show the presence of indole alkaloids are Piper methysticum G. Forst (kava) and Valeriana officinalis L., deserve special attention. Chemical structure of isolated compounds from these plants can be used as the basis for the development of new drugs.
Which drug is indole derivative?
Indole Derivatives
| Drug | Drug Description |
|---|---|
| Ziprasidone | An atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia. |
| Molindone | An antipsychotic used to treat schizophrenia. |
| Sertindole | An atypical antipsychotic indicated in the treatment of schizophrenia. |
Which drug is under the chemical class of indole?
… best-known indole-containing compounds are the indole alkaloids, which have been isolated from plants representing more than 30 families. The mushroom hallucinogens psilocin and psilocybin, the ergot fungus alkaloids, the drugs reserpine and yohimbine, and the poison strychnine all belong to this group.
Which drug contain indole ring?
Most drugs on the market contain the indole substructure. These include indomethacin, ergotamine, frovatriptan, ondansetron, and tadalafil.
Where is indole found?
Indole is a solid at room temperature. It occurs naturally in human feces and has an intense fecal odor. At very low concentrations, however, it has a flowery smell, and is a constituent of many perfumes. It also occurs in coal tar.
What is the use of indole?
Indole-3-carbinol is a substance found in vegetables such as broccoli, Brussels sprouts, cabbage, collards, cauliflower, kale, mustard greens, turnips, and rutabagas. It can also be produced in the laboratory. Indole-3-carbinol is used for prevention of breast cancer, colon cancer, and other types of cancer.
What are Bisindole alkaloids? Bisindole natural products consist of two monomeric indole alkaloid units as their obligate constituents. Bisindoles are more potent with respect to their biological activity than their corresponding monomeric units. The monomeric units belong to the sarpagine, ajmaline, macroline, vobasine, and pleiocarpamine series. What is Bisindole? Noun. bisindole (plural bisindoles) (organic chemistry)…