What happens if you touch Mitomycin?

* Contact can irritate the skin and eyes. * High exposure may cause poor appetite, fever, nausea, headache, fatigue and drowsiness. * Repeated contact can cause severe eye damage. * Repeated high exposure may affect the liver, kidneys and blood cells.

How do you dispose of Mitomycin?

DISPOSING OF MITOMYCIN C Dispose of MMC container, soaked sponges, and surgical waste materials that have come in contact with MMC (gowns, gloves, patient drapes) in an appropriate chemotherapy disposal container. Wear appropriate Personal Protective Equipment including gloves, mask, face shield and impervious gown.

Is Mitomycin cytotoxic?

Drug type: Mitomycin is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. This medication is classified as an “antitumor antibiotic.” (For more detail, see “How this drug works” section below).

Is Mitomycin a Vesicant?

Mitomycin C is a vesicant chemotherapeutic agent used to treat solid tumors. Its ability to cause delayed and remote tissue injury after intravenous administration is reported in the literature.

Does mitomycin make you tired?

Common side effects of Mutamycin (mitomycin) include nausea and vomiting (may be severe), stomach/abdominal pain, loss of appetite, headache, blurred vision, drowsiness, dizziness, or weakness.

Can mitomycin cause hair loss?

Mitomycin sometimes causes a temporary loss of hair. After treatment has ended, normal hair growth should return. After you stop using this medicine, it may still produce some side effects that need attention.

How long does mitomycin stay in your system?

Mitomycin is a chemotherapy drug that aims to kill any cancer cells that may have remained in your bladder after surgery. The drug itself stays in your bladder for one to two hours and is then drained out through the urinary catheter, or leaves your bladder when you pass urine.

What are the side effects of mitomycin?

Mitomycin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

nausea.
vomiting.
loss of appetite or weight.
sores in the mouth and throat.
headache.
fainting.
blurred vision.
hair loss.

Is Mitomycin a chemo drug?

Mitomycin is a chemotherapy drug used to treat different cancers including breast, bladder, stomach, pancreatic, anal and lung cancers.

Can Mitomycin cause hair loss?

Does mitomycin cause weight gain?

Mitomycin can damage red blood cells, which may cause irreversible kidney failure. Tell your doctor right away if you have unusual bruising or bleeding, pale skin, confusion, tiredness or irritability, stomach pain, bloody diarrhea, red or pink urine, swelling, rapid weight gain, and little or no urinating.

What is the concentration of mitomycin after injection?

After injection of 30 mg, 20 mg, or 10 mg intravenous., the maximal serum concentrations were 2.4 mcg/mL, 1.7 mcg/mL, and 0.52 mcg/mL, respectively. Clearance is effected primarily by metabolism in the liver, but metabolism occurs in other tissues as well.

How long does it take to remove mitomycin from the body?

At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed. In humans, Mitomycin is rapidly cleared from the serum after intravenous administration. Time required to reduce the serum concentration by 50% after a 30 mg bolus injection is 17 minutes.

When to use mitomycin in blood transfusions?

The syndrome may occur at any time during systemic therapy with mitomycin as a single agent or in combination with other cytotoxic drugs, however, most cases occur at doses ≥60 mg of mitomycin. Blood product transfusion may exacerbate the symptoms associated with this syndrome.

How is mitomycin handled as a vesicant?

Mitomycin is a vesicant. If preparation cannot be performed in a biocontainment hood, then a mask and double gloves should be worn and mixed in a closed system drug transfer device. 3. All equipment, supplies and receptacles in contact with cytotoxic agents are handled and disposed of as chemotherapy waste. C. Gemcitabine: 1.

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What happens if you touch Mitomycin? * Contact can irritate the skin and eyes. * High exposure may cause poor appetite, fever, nausea, headache, fatigue and drowsiness. * Repeated contact can cause severe eye damage. * Repeated high exposure may affect the liver, kidneys and blood cells. How do you dispose of Mitomycin? DISPOSING OF…